A list containing
known.confThe known confounders matrix which is adjusted in all mediation tests. Each row is a confounder, each column is a sample.
cov.poolThe pool of candidate confounding variables from which potential confounders are adaptively selected to adjust for each mediation test. Each row is a covariate, each column is a sample.
exp.datThe gene expression matrix. Each row is for one gene, each column is a sample.
snp.dat.cisThe cis-eQTL genotype matrix. Each row is an eQTL, each column is a sample.
trios.idxThe matrix of selected trios indexes (row numbers) for mediation tests. Each row consists of the index (i.e., row number) of the eQTLs in snp.dat.cis
,
the index of cis-gene transcript in exp.dat
, and the index of trans-gene transcript in exp.dat
. The dimension is the number of trios by three.