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GeneReg (version 1.1.2)

timedelay.lm: time delay linear model

Description

timedelay.lm is for time delay linear model.

Usage

timedelay.lm(bspline.data, expr.data, target, regulator, maxdelay=ncol(bspline.data)*0.25, single.adj.r.squared=0.8, multiple.adj.r.squared=0.9, min.coef=0.25, max.coef=4, output=FALSE, topdf=FALSE, xlab='time point', ylab='log ratio')

Arguments

bspline.data
an interpolated expression matrix with genes in the rows, predicted time points in the columns
expr.data
an observed expression matrix with genes in the rows, predicted time points in the columns
target
target gene
regulator
potential regulators
maxdelay
max time points delay
single.adj.r.squared
the cutoff of adjusted R squared of univariate regression
multiple.adj.r.squared
the cutoff of adjusted R squared of multivariate regression
min.coef
the regression coefficient should be larger than min.coef
max.coef
the regression coefficient should be smaller than max.coef
output
whether the model should be plotted
topdf
whether the model should be plotted into a pdf file
xlab
xlab of the plot
ylab
ylab of the plot

References

Tao Huang, Lei Liu, Ziliang Qian, Kang Tu, Yixue Li, Lu Xie: Using GeneReg to construct time delay gene regulatory networks. BMC Res Notes 2010, 3(1):142. http://www.biomedcentral.com/1756-0500/3/142