GeneReg (version 1.1.2)

timedelay.univariate.lm: Internal function for time delay linear model

Description

timedelay.univariate.lm is an internal function for time delay linear model.

Usage

timedelay.univariate.lm(bspline.data, target, regulator,
maxdelay=ncol(bspline.data)*0.25,
single.adj.r.squared=0.8, min.coef=0.25, max.coef=4)

Arguments

bspline.data

an interpolated expression matrix with genes in the rows, predicted time points in the columns

target

target gene

regulator

potential regulators

maxdelay

max time points delay

single.adj.r.squared

the cutoff of adjusted R squared of univariate regression

min.coef

the regression coefficient should be larger than min.coef

max.coef

the regression coefficient should be smaller than max.coef

References

Tao Huang, Lei Liu, Ziliang Qian, Kang Tu, Yixue Li, Lu Xie: Using GeneReg to construct time delay gene regulatory networks. BMC Res Notes 2010, 3(1):142. http://www.biomedcentral.com/1756-0500/3/142