Simulation of Single Cell RNA-Seq Data with Complex Structure
Description
Simulating single cell RNA-seq data with complicated structure. This package is developed based on the Splat method (Zappia, Phipson and Oshlack (2017) ). 'GeneScape' incorporates additional features to simulate single cell RNA-seq data with complicated differential expression and correlation structures, such as sub-cell-types, correlated genes (pathway genes) and hub genes.