fcsim

This function similate differential expression fold change level

Simulating single cell RNA-seq data with complicated structure. This package is developed based on the Splat method (Zappia, Phipson and Oshlack (2017) <doi:10.1186/s13059-017-1305-0>). 'GeneScape' incorporates additional features to simulate single cell RNA-seq data with complicated differential expression and correlation structures, such as sub-cell-types, correlated genes (pathway genes) and hub genes.

Qi Gao

GeneScape

Simulation of Single Cell RNA-Seq Data with Complex Structure

fcsim function

<dl><dt>n.gene</dt>
<dd>total number of genes</dd>
<dt>de.id</dt>
<dd>index of differentially expressed genes</dd>
<dt>fc.loc</dt>
<dd>location parameter for fold change (log-normal distribution)</dd>
<dt>fc.scale</dt>
<dd>scale parameter for fold change (log-normal distribution)</dd></dl>

Arguments

fcsim — fcsim

<dl>

<dt>n.gene</dt>
<dd>total number of genes</dd>


<dt>de.id</dt>
<dd>index of differentially expressed genes</dd>


<dt>fc.loc</dt>
<dd>location parameter for fold change (log-normal distribution)</dd>


<dt>fc.scale</dt>
<dd>scale parameter for fold change (log-normal distribution)</dd>

</dl>

fcsim: fcsim

Description

Usage

Arguments

References