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HBP (version 0.1.2)

Hi-C BED File Analysis Pipeline

Description

Hi-C dataset processing algorithm introduced by Chao He (2016) . The optimized and flexible pipeline for analyzing the folding of whole chromosome and interactions between some specific sites from the Hi-C raw sequencing reads to the partially processed datasets. The other complex genetic and epigenetic datasets from public sources such as GWAS, ENCODE consortiums etc. will also easily be integrated into HBP, hence the final output results of HBP could provide a comprehensive in-depth understanding for the specific chromatin interactions, potential molecular mechanisms and biological significance. We believe that HBP is a reliable tool for the rapidly analysis of Hi-C data and will be very useful for a wide range of researchers, particularly those who lack of background in computational biology.

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Version

Install

install.packages('HBP')

Monthly Downloads

4

Version

0.1.2

License

GPL (>= 2)

Maintainer

Chao He

Last Published

July 7th, 2017

Functions in HBP (0.1.2)

circos_plot

Visualization of interactions and tracks
convert_bed_to_matrix

convert the bed file to matrix file for the next analysis
check_bed_bin

process the bed file data to bin
choose_chr_bed

choose which chrom from the BED file
find_bed_to_bed_interaction

find the interaction between specific sites
find_bed_to_bed_interaction_solo

help find_bed_to_bed_interaction finish its work
calculate_omiccircos_data

output the interaction that our bed interact with ourbed.
calculate_omiccircos_data_solo

help calculate_omiccircos_data to finish its work
run_hicpro

run the hic-pro
generate_enzyme_file

generate enzyme file
generate_matrix

generate matrix files
whitered

generate the color of heatmap
statistical_analysis

Statistical significance tests
if_distribution_analysis

analyse the interaction frequency distribution
load_all_wig

the function to load wig file
load_bed

the function to load bed file
load_bed_wig

the function to load wig file in the specific sites
load_wig

the function to load tracks
network_analysis

Interaction network topological analysis