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IPPD (version 1.20.0)

Isotopic peak pattern deconvolution for Protein Mass Spectrometry by template matching

Description

The package provides functionality to extract isotopic peak patterns from raw mass spectra. This is done by fitting a large set of template basis functions to the raw spectrum using either nonnegative least squares or least absolute deviation fittting. The package offers a flexible function which tries to estimate model parameters in a way tailored to the peak shapes in the data. The package also provides functionality to process LCMS runs.

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Version

Version

1.20.0

License

GPL (version 2 or later)

Maintainer

Martin Slawski

Last Published

February 15th, 2017

Functions in IPPD (1.20.0)

read.mzXML

Import of data in mzXML format
myo500

Myoglobine dataset
getPeaklist

Peak pattern extraction by non-negative ls/lad template matching
IPPD-package

Peak pattern deconvolution for Protein Mass Spectrometry by non-negative ls/lad template matching
peaklist-class

"Peaklist"
fitModelParameters

Peak parameter estimation
sweepline

Sweep line scheme to process LC-MS data
internals

Internal functions
toyspectrum

Simulated protein mass spectrum
modelfit-class

"Modelfit"
analyzeLCMS

Functionality for LC-MS data