KSEA.Scores.2

A sample KSEA.Scores output generated from the KSEA.Scores() function 
(or alternatively, the &quot;KSEA Kinase Scores.csv&quot; output from the KSEA.Complete() function, loaded into R)

datasets

Infers relative kinase activity from phosphoproteomics data
using the method described by Casado et al. (2013) <doi:10.1126/scisignal.2003573>.

Danica Wiredja

KSEAapp

Kinase-Substrate Enrichment Analysis

KSEA.Scores.2 function

dataframe containing 7 columns in the exact order as listed below.
            <ul>
<li>&quot;KinaseGene&quot; the HUGO gene name of the kinase
                </li>
<li>&quot;mS&quot; the mean log2FC of all the kinase&#39;s identified substrates
                </li>
<li>&quot;Enrichment&quot; the enrichment score (refer to Casado et al. (2013) Sci. Signal., 6, rs6-rs6)
                </li>
<li>&quot;m&quot; the number of experimentally-identifed substrates annotating to that kinase
                </li>
<li>&quot;z.score&quot; the normalized kinase score
                </li>
<li>&quot;p.value&quot; the statistical assessment of the kinase score
                </li>
<li>&quot;FDR&quot; the p-value adjusted for multiple hypothesis testing by the Benjamin-Hochberg method
             </li>
</ul>

KSEA.Scores.2: One of the 3 datasets for heatmap plotting

Description

Usage

Arguments

Format

References