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MBMethPred (version 0.1.4.2)

Medulloblastoma Subgroups Prediction

Description

Utilizing a combination of machine learning models (Random Forest, Naive Bayes, K-Nearest Neighbor, Support Vector Machines, Extreme Gradient Boosting, and Linear Discriminant Analysis) and a deep Artificial Neural Network model, 'MBMethPred' can predict medulloblastoma subgroups, including wingless (WNT), sonic hedgehog (SHH), Group 3, and Group 4 from DNA methylation beta values. See Sharif Rahmani E, Lawarde A, Lingasamy P, Moreno SV, Salumets A and Modhukur V (2023), MBMethPred: a computational framework for the accurate classification of childhood medulloblastoma subgroups using data integration and AI-based approaches. Front. Genet. 14:1233657. for more details.

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Install

install.packages('MBMethPred')

Monthly Downloads

186

Version

0.1.4.2

License

GPL

Issues

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Maintainer

Edris Sharif Rahmani

Last Published

September 18th, 2023

Functions in MBMethPred (0.1.4.2)

LinearDiscriminantAnalysisModel

Linear discriminant analysis model
NaiveBayesModel

Naive bayes model
ModelMetrics

Model metrics
XGBoostModel

XGBoost model
KNearestNeighborModel

K nearest neighbor model
Data3

Data3
ReadSNFData

Input file for similarity network fusion (SNF)
SimilarityNetworkFusion

Similarity network fusion (SNF)
NeuralNetworkModel

Artificial neural network model
RandomForestModel

Random forest model
ReadMethylFile

Input file for prediction
SupportVectorMachineModel

Support vector machine model
Data1

Training data
Data2

Data2
NewDataPredictionResult

New data prediction result
RLabels

RLabels
TSNEPlot

t-SNE 3D plot
BoxPlot

Box plot
ConfusionMatrix

Confusion matrix