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MDR (version 1.2)

Detect gene-gene interactions using multifactor dimensionality reduction

Description

Performs multifactor dimensionality reduction (MDR) to detect potential gene-gene interactions in case-control studies.

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Version

Install

install.packages('MDR')

Monthly Downloads

12

Version

1.2

License

GPL-2

Maintainer

Stacey Winham

Last Published

March 12th, 2012

Functions in MDR (1.2)

mdr.hr

Function to estimate the accuracy of an MDR model given high-risk/low-risk status of genotype combinations
MDR-package

Detect gene-gene interactions using multifactor dimensionality reduction
mdr.3WS

A function to perform MDR on a dataset using the three-way split for internal validation.
boot.error

Function to calculate a post-hoc prediction estimate of classification error adjusted for population prevalence using bootstrap resampling
compare

Function for internal use only ...
mdr.ca.adj

Function to calculate a post-hoc adjusted prediction estimate of classification accuracy, corrected for prospective data with previously estimated population prevalence
mdr2

Sample data for MDR package for n=250, p=100
mdr1

Sample data for MDR package for n=250, p=25
mdr.cv

A function to perform MDR on a dataset using k-fold cross-validation for internal validation.
mdr

Function to perform MDR on a dataset for a given set of loci
permute.mdr

Function to perform a permutation test after fitting an MDR model
predict.mdr

MDR model predictions
plot.mdr

Plotting the results of an MDR model
train

Sample data for MDR package for n=1000, p=5000
test

Sample data for MDR package for n=1000, p=5000
summary.mdr

Summarizing the results of an MDR model