MTAR (version 0.1.1)

Get_UV_from_varU: Compute the summary statistics given the score statistics and their variance.

Description

This function allows you to calculate the score summary statistics \(U\) and their covariance matrix \(V\) for MTAR, given the score summary statistics and their variance.

Usage

Get_UV_from_varU(U, varU, R)

Arguments

U

a numeric list, each sublist containing score summary statistics \(U\) for each study. In each study, a numeric \(m \times K\) matrix with each row as a SNP and each column as a separate trait. The number of traits and the number of SNPs in each study can be different but their names are required.

varU

a numeric list, each sublist containing the variance of score summary statistics information for each study. In each study, a numeric \(m \times K\) matrix with each row as a SNP and each column as a separate trait.

R

a SNP correlation matrix, which should contain the correlation of all the SNPs in these studies.

Value

A list containing summary statistics for each traits, the score summary statistics \(U\) and their covariance matrix \(V\).

Examples

# NOT RUN {
data("varU.example")
attach(varU.example)
obs.stat <- Get_UV_from_varU(U = U, varU = varU, R= R)
obs.stat
detach(varU.example)
# }