NMTox (version 0.1.0)

SplitData: Split the data of each nanomaterial into different subsets of data

Description

This function splits the data of each nanomaterial into different subsets of data according to the unique values of selected variable(s)

Usage

SplitData(data.nm, data.control, id, nano, dose, end, end.cat, unit,
  unit.cat, control.opt=c("same","all"), vars)

Value

This function splits the data of each nanomaterial into different subsets of data according to the unique values of selected variable(s)

Arguments

data.nm

Data containing the result of toxicity study

data.control

Data of control values

id

Identifier of the experiment

nano

Name of the nanomaterial

dose

Dose or concentration

end

Toxicity endpoint

end.cat

Specific toxicity endpoint of interest

unit

Unit of measurement of the dose

unit.cat

Specific unit of measurement of the dose

control.opt

Option for the control doses if unit and unit.cat are specified. If only control doses with the same unit of measurement as the non-control ones are included, then specify "same" in the control.opt. If all control doses with any units of measurement are included, then specify "all".

vars

Variables used to split the data

Examples

# Example 1:
# Create a dataset containing controls (which are named differently)
# from geninvitro dataset:
controldata<-SubsetData(data=geninvitro, x="name", x.cat=c("control", "Control",
             "medium", "medium + BSA", "untreated"))

# Exclude controls (which are named differently) from geninvitro dataset:
invitrodata<-SubsetData(data=geninvitro, x="name", x.cat=c("control", "Control",
             "medium", "medium + BSA", "untreated"), include=FALSE)
#
# Split geninvitro data according to the cell type, method, study provider,
# unit of the concentration and the type of the endpoint:
datasub<-SplitData(data.nm=invitrodata, data.control=controldata,
                   id="experimentID", nano="name", dose="concentration",
                   vars=c("celltype", "method","studyprovider",
                   "concentration_unit","endpoint"))

# Example 2:
# Split geninvitro data with DNA STRAND BREAKS as the endpoint, according
# to the cell type, method, study provider, and unit of the concentration:
datasub2<-SplitData(data.nm=invitrodata, data.control=controldata,
                    id="experimentID", nano="name", dose="concentration",
                    end="endpoint", end.cat="DNA STRAND BREAKS",
                    vars=c("celltype","method","studyprovider",
                    "concentration_unit"))

# Example 3:
# Split geninvitro data with DNA STRAND BREAKS as the endpoint and
# concentration measured in ug/cm2, according to the cell type:
datasub3<-SplitData(data.nm=invitrodata, data.control=controldata,
                    id="experimentID", nano="name", dose="concentration",
                    end="endpoint", end.cat="DNA STRAND BREAKS",
                    unit="concentration_unit", unit.cat="ug/cm2",
                    control.opt="same", vars="celltype")