nm400

This dataset contains the result of genetic toxicity in vitro study of NM-400
(Multi-walled carbon nanotubes) with associated controls and variables
related to the experiments.

datasets

Perform an exploration and a preliminary analysis on the dose-
response relationship of nanomaterial toxicity. Several functions are
provided for data exploration, including functions for creating a subset of
dataset, frequency tables and plots. Inference for order restricted dose-
response data is performed by testing the significance of monotonic
dose-response relationship, using Williams, Marcus, M, Modified M and
Likelihood ratio tests. Several methods of multiplicity adjustment
are also provided. Description of the methods can be found in <https://github.com/rahmasarina/dose-response-analysis/blob/main/Methodology.pdf>.

Rahmasari Nur Azizah

NMTox

Dose-Response Relationship Analysis of Nanomaterial Toxicity

Geert Verheyen

Sabine Van Miert

Ziv Shkedy

nm400 function

A data frame with columns:<ul>
<li>name: Project-assigned name of the nanomaterial</li>
<li>publicname: A widely accepted unique identifier</li>
<li>supplier: Supplier/project where the data is originated from</li>
<li>experimentID: Identifier of the experiment</li>
<li>method: Method/assay used in the experiment</li>
<li>studyprovider: Study provider</li>
<li>endpoint: Toxicity endpoint measure</li>
<li>value: Endpoint value</li>
<li>unit: Unit of the endpoint</li>
<li>celltype: Type of the cell used in the experiment</li>
<li>treatment: Indicator of the treatment</li>
<li>exptimeunit: Unit of measurement of the exposure time</li>
<li>exptime: Exposure time</li>
<li>concentration_unit: Unit of measurement of the concentration in
 variable concentration</li>
<li>concentration: Concentration of the nanomaterial</li>
<li>concentration_ml_unit: Unit of measurement of the concentration
 in variable concentration_ml</li>
<li>concentration_ml: Concentration of the nanomaterial in amount per
 ml</li>
</ul>

Format

NM-400 in vitro dataset — nm400

NM-400 in vitro dataset

nm400: NM-400 in vitro dataset

Description

Usage

Arguments

Format

Examples