A numeric vector. Model parameter values

A numeric. ith dose level for a given design

A numeric. jth dose level for a given design

A numeric. last dose level for a given design

A numeric matrix. Inverse of the information matrix

numeric. The number of model paraemters

order

This function computes each element of the matrix function c_weight_2 which is the second derivative of the c-optimality criterion with respect to the model parameters.

Obtain and evaluate various optimal designs for the 3, 4, and 5-parameter logistic models. The optimal designs are obtained based on the numerical algorithm in Hyun, Wong, Yang (2018) <doi:10.18637/jss.v083.i05>.

DD1: Computing each element of the function c_weight_2

Description

Usage

Arguments