This computes the second derivative of the D-optimality criterion with respect to the model parameters for a specified model.
smalldd1(T, x1, x2, xl, inv, order)
A numeric vector. Model parameter values
A numeric. ith dose level
A numeric. jth dose level
A numeric. last dose level
A numeric matrix. Inverse information matrix
numeric. The number of model paraemters: 3, 4, 5 for the 3, 4, 5PL models respectively