PoweREST (version 0.1.2)

A Bootstrap-Based Power Estimation Tool for Spatial Transcriptomics

Description

Power estimation and sample size calculation for 10X Visium Spatial Transcriptomics data to detect differential expressed genes between two conditions based on bootstrap resampling. See Shui et al. (2025) for method details.

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Version

Install

install.packages('PoweREST')

Monthly Downloads

155

Version

0.1.2

License

MIT + file LICENSE

Maintainer

Lan Shui

Last Published

December 9th, 2025

Functions in PoweREST (0.1.2)

fit_XGBoost

Fit with XGBoost

PoweREST_subset

Bootstrap resampling and power calculation for a subset of genes

pred_XGBoost

Prediction results from XGBoost

PoweREST

Bootstrap resampling and power calculation upon ST data

pred_powerest

Power value prediction

PoweREST_gene

Bootstrap resampling and power estimation for one single gene

power_example

An example of power results with multiple replicates number

fit_powerest

Fit the power surface

plotly_powerest

3D interactive visualization

vis_powerest

Visualization of the power surface

vis_XGBoost

Visualization of the power estimations from XGBoost

%>%

Pipe operator

result_example

An example of power results from PoweREST