getData

<p>String. These example data are included: mRNA_path, microRNA_path, drug.ic50, drug.r, drug.fdr, drug.info, drug.edgelist, breast_cancer and brc_candidates.</p>

exampleData

<p>This function is used to get example data.</p>

Prioritize candidate cancer drugs for drug repositioning based on the random walk with restart algorithm in a drug-drug functional similarity network. 1) We firstly constructed a drug-drug functional similarity network by integrating pathway activity and drug activity derived from the NCI-60 cancer cell lines. 2) Secondly, we calculated drug repurposing score according to a set of approved therapeutic drugs of interested cancer based on the random walk with restart algorithm in the drug-drug functional similarity network. 3) Finally, the permutation test was used to calculate the statistical significance level for the drug repurposing score.

getData: getData

Description

Usage

Arguments