Enrichment for Diseases in a Set of Genes
Description
It provides a list of genes associated to diseases (g2d$clean and g2d$complete) based on the following 4 publications (GS2D, Fontaine (2016) , DisGeNET, Pinero (2016) Berto2016, Berto (2016) and PsyGeNET, Sacristan (2015) ). Those lists were combined and manually curated to have matching disease names. When provided a list of gene names, it calculates the disease enrichment of the gene set. The enrichment is calculated using proportion test and Fisher's exact test. Adjusted fdr p-values are returned alongside with p-values combined using the Fisher's method.