conduct.phase3

This function is used to estimate the effect size of the selected
subgroup.

Design a Bayesian seamless multi-arm biomarker-enriched phase II/III
design with the survival endpoint with allowing sample size re-estimation.
James M S Wason, Jean E Abraham, Richard D Baird, Ioannis Gournaris, Anne-Laure Vallier, James D Brenton, Helena M Earl, Adrian P Mander (2015) <doi:10.1038/bjc.2015.278>.
Guosheng Yin, Nan Chen, J. Jack Lee (2018) <doi:10.1007/s12561-017-9199-7>.
Ying Yuan, Beibei Guo, Mark Munsell, Karen Lu, Amir Jazaeri (2016) <doi:10.1002/sim.6971>.

Chengxue Zhong

SAME

Seamless Adaptive Multi-Arm Multi-Stage Enrichment

Haitao Pan

Hongyu Miao

conduct.phase3 function

<dl><dt>data</dt>
<dd>a data.frame in which to interpret the variables named in the formula</dd>
<dt>eta</dt>
<dd>a cutoff probability for the strength of evidence for decision-making</dd>
<dt>theta</dt>
<dd>a clinically meaningful treatment effect size defined by clinicians</dd></dl>

Arguments

Function to estimate the hazard ratios and other statistics of the selected
subgroup — conduct.phase3

<dl>

<dt>data</dt>
<dd>a data.frame in which to interpret the variables named in the formula</dd>


<dt>eta</dt>
<dd>a cutoff probability for the strength of evidence for decision-making</dd>


<dt>theta</dt>
<dd>a clinically meaningful treatment effect size defined by clinicians</dd>

</dl>

conduct.phase3: Function to estimate the hazard ratios and other statistics of the selected subgroup

Description

Usage

Value

Arguments

Examples