example.2

A Time-to-event dataset containing the time and other attributes of 643 patients.

datasets

Design a Bayesian seamless multi-arm biomarker-enriched phase II/III
design with the survival endpoint with allowing sample size re-estimation.
James M S Wason, Jean E Abraham, Richard D Baird, Ioannis Gournaris, Anne-Laure Vallier, James D Brenton, Helena M Earl, Adrian P Mander (2015) <doi:10.1038/bjc.2015.278>.
Guosheng Yin, Nan Chen, J. Jack Lee (2018) <doi:10.1007/s12561-017-9199-7>.
Ying Yuan, Beibei Guo, Mark Munsell, Karen Lu, Amir Jazaeri (2016) <doi:10.1002/sim.6971>.

Chengxue Zhong

SAME

Seamless Adaptive Multi-Arm Multi-Stage Enrichment

Haitao Pan

Hongyu Miao

example.2 function

A data frame with 643 rows and 6 variables:<dl>
<dt>T1</dt>
<dd>binary variable, receive treatment 1=1, not receive treatment 1=0</dd><dt>T2</dt>
<dd>binary variable, receive treatment 2=1, not receive treatment 2=0</dd><dt>B1</dt>
<dd>binary variable, biomarker 1 positive=1, biomarker 1 negative=0</dd><dt>B2</dt>
<dd>binary variable, biomarker 2 positive=1, biomarker 2 negative=0</dd><dt>death</dt>
<dd>the status indicator, alive=0, dead=1</dd><dt>surv</dt>
<dd>survival time or follow up time</dd><dt>survtime</dt>
<dd>survival time or follow up time</dd><dt>treatments</dt>
<dd>categorical vairable, indicating treatments received</dd>...</dl>

Format

A Time-to-event dataset containing the time and other attributes of 643 patients. — example.2

A data frame with 643 rows and 6 variables:<dl>
<dt>T1</dt>
<dd>binary variable, receive treatment 1=1, not receive treatment 1=0</dd>

<dt>T2</dt>
<dd>binary variable, receive treatment 2=1, not receive treatment 2=0</dd>

<dt>B1</dt>
<dd>binary variable, biomarker 1 positive=1, biomarker 1 negative=0</dd>

<dt>B2</dt>
<dd>binary variable, biomarker 2 positive=1, biomarker 2 negative=0</dd>

<dt>death</dt>
<dd>the status indicator, alive=0, dead=1</dd>

<dt>surv</dt>
<dd>survival time or follow up time</dd>

<dt>survtime</dt>
<dd>survival time or follow up time</dd>

<dt>treatments</dt>
<dd>categorical vairable, indicating treatments received</dd>

...

</dl>

example.2: A Time-to-event dataset containing the time and other attributes of 643 patients.

Description

Usage

Arguments

Format