STRINGdb (version 1.10.0)

remove_homologous_interactions: remove_homologous_interactions

Description

With this method it is possible to remove the interactions that are composed by a pair of homologous/similar proteins, having a similarity bitscore between each other higher than a threshold.

Usage

"remove_homologous_interactions"(interactions_dataframe, bitscore_threshold = 60)

Arguments

interactions_dataframe

a data frame contaning the sorted interactions to be benchmarked. The data frame should have the following column names: proteinA, proteinB, score

bitscore_threshold

filter out pairs of homologous proteins, having a similarity bitscore higher than this parameter

Value

interactions data frame where the homologous pairs have been removed, from the input interactions' data frame