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SeqFeatR (version 0.3.3)

A Tool to Associate FASTA Sequences and Features

Description

Provides user friendly methods for the identification of sequence patterns that are statistically significantly associated with a property of the sequence. For instance, SeqFeatR allows to identify viral immune escape mutations for hosts of given HLA types. The underlying statistical method is Fisher's exact test, with appropriate corrections for multiple testing, or Bayes. Patterns may be point mutations or n-tuple of mutations. SeqFeatR offers several ways to visualize the results of the statistical analyses, see Budeus (2016) .

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Version

Install

install.packages('SeqFeatR')

Monthly Downloads

223

Version

0.3.3

License

GPL (>= 3)

Maintainer

Bettina Budeus

Last Published

February 13th, 2026

Functions in SeqFeatR (0.3.3)

orPlot

Visualize odds ratios and p-values from SeqFeatRs assocpoint
q-values

Calculate q-values from p-values
smallmanhattan

A small version of manhattan plot
rewritetuple

Rewrite result from SeqFeatRs assoctuple
assoctuple

Searches for associations of a tuple of alignment positions with feature(s)
SeqFeatRGUI

GUI for SeqFeatR
foundereffectfinder

Tries to identify a founder effect in results from SeqFeatRs assocpair
comparewithancestral

Compares ancestral sequence with sequence alignment
assocpairfeat

Finding pairs of sequence alignment positions associated with sequence feature.
getfreqs

Get frequencies for amino acids/nucleotides in alignment window (epitope)
assocpoint

Searches for associations of single alignment positions with feature(s)
assocpair

Finding pairs of alignment positions that jointly mutate
assocpointpair

Compare results of SeqFeatRs assocpoint with SeqFeatRs assocpair, assocpairfeat
assocpointhierarchical

Searches for associations of single alignment positions with feature(s) with a simple hierarchical model
visualizepairfeat

Visualize pairs of sequence alignment positions associated with sequence feature.
visualizepair

Visualize pairs of alignment positions that jointly mutate
tartan

Visualize association of mutation pairs and features from two (comparable) analyses.
volcanoplot

Create volcano plot