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TDCor (version 0.1-2)

Gene Network Inference from Time-Series Transcriptomic Data

Description

The Time-Delay Correlation algorithm (TDCor) reconstructs the topology of a gene regulatory network (GRN) from time-series transcriptomic data. The algorithm is described in details in Lavenus et al., Plant Cell, 2015. It was initially developed to infer the topology of the GRN controlling lateral root formation in Arabidopsis thaliana. The time-series transcriptomic dataset which was used in this study is included in the package to illustrate how to use it.

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Version

Install

install.packages('TDCor')

Monthly Downloads

119

Version

0.1-2

License

GPL (>= 2)

Maintainer

Mikael Lucas

Last Published

October 26th, 2015

Functions in TDCor (0.1-2)

UpdateDPI

Update or check the DPI database
TF

Table of 1834 Arabidopsis Transcription factors
shortest.path

Calculate the shortest path linking every pairs of nodes in the network
times

The times vector to use with the lateral root dataset
TDCor-package

TDCor algorithm for gene regulatory network inference
l_genes

l_genes
LR_dataset

Lateral root transcriptomic dataset
l_names

l_names
l_prior

l_prior
TDCOR

The TDCOR main function
UpdateTPI

Update or check the TPI database
CalculateDPI

Generate the DPI database to be used by the TDCOR main function
CalculateTPI

Generate the TPI database to be used by the TDCOR main function
draw.profile

Plot the expression profile of a gene in dataset
estimate.delay

Estimate the time shift between two gene profiles and make a plot
clean.at

Elimininate from a vector of gene codes the genes for which no data is available.