check_RET_arguments

Check arguments for their respective condition

Design and analyze three-arm non-inferiority or superiority trials
which follow a gold-standard design, i.e. trials with an experimental treatment,
an active, and a placebo control. Method for the following distributions are implemented:
Poisson (Mielke and Munk (2009) <arXiv:0912.4169>), negative binomial (Muetze et al. (2016) <doi:10.1002/sim.6738>),
normal (Pigeot et al. (2003) <doi:10.1002/sim.1450>; Hasler et al. (2009) <doi:10.1002/sim.3052>),
binary (Friede and Kieser (2007) <doi:10.1002/sim.2543>), nonparametric (Muetze et al. (2017) <doi:10.1002/sim.7176>),
exponential (Mielke and Munk (2009) <arXiv:0912.4169>).

Tobias Muetze

ThreeArmedTrials

Design and Analysis of Clinical Non-Inferiority or Superiority
Trials with Active and Placebo Control

Tobias Mütze

Tim Friede

check_RET_arguments function

<dl><dt>sig.level</dt>
<dd>A numeric value specifying the significance level (type I error probability)</dd>
<dt>power</dt>
<dd>A numeric value specifying the target power (1 - type II error probability)</dd>
<dt>Delta</dt>
<dd>A numeric value specifying the non-inferiority or superiority margin.
Is between 0 and 1 in case of non-inferiority and larger than 1 in case of superiority.</dd>
<dt>n</dt>
<dd>The total sample size. Needs to be at least 7.</dd>
<dt>allocation</dt>
<dd>A (non-empty) vector specifying the sample size allocation (nExp/n, nRef/n, nPla/n)</dd></dl>

Arguments

check_RET_arguments — check_RET_arguments

<dl>

<dt>sig.level</dt>
<dd>A numeric value specifying the significance level (type I error probability)</dd>


<dt>power</dt>
<dd>A numeric value specifying the target power (1 - type II error probability)</dd>


<dt>Delta</dt>
<dd>A numeric value specifying the non-inferiority or superiority margin.
Is between 0 and 1 in case of non-inferiority and larger than 1 in case of superiority.</dd>


<dt>n</dt>
<dd>The total sample size. Needs to be at least 7.</dd>


<dt>allocation</dt>
<dd>A (non-empty) vector specifying the sample size allocation (nExp/n, nRef/n, nPla/n)</dd>

</dl>

check_RET_arguments: check_RET_arguments

Description

Usage

Arguments