TrialSize (version 1.4)

OneSampleProportion.Equivalence: One sample proportion test for equivalence

Description

Ho: \( |p-p0| \ge margin \)

Ha: |p-p0| < margin

The proportion of response is equivalent to the reference p0 is the null hypothesis is rejected

Usage

OneSampleProportion.Equivalence(alpha, beta, p, delta, differ)

Arguments

alpha

significance level

beta

power = 1-beta

p

the true response rate

delta

delta=p-p0

the difference between the true response rate of a test drug and a reference value p0

differ

the superiority or non-inferiority margin

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

Examples

# NOT RUN {
Example.4.1.4<-OneSampleProportion.Equivalence(0.05,0.2,0.6,0.05,.2)
Example.4.1.4

# }