TrialSize (version 1.4)

RelativeRisk.Equivalence: Relative Risk in Parallel Design test for Equivalence

Description

Ho: \(|log(OR)| \ge margin \)

Ha: |log(OR)| < margin

Usage

RelativeRisk.Equivalence(alpha, beta, or, k, pt, pc, margin)

Arguments

alpha

significance level

beta

power = 1-beta

or

or=pt(1-pc)/pc(1-pt)

k

k=nT/nC

pt

the probability of observing an outcome of interest for a patient treatment by a test treatment

pc

the probability of observing an outcome of interest for a patient treatment by a control

margin

the superiority or non-inferiority margin

References

Chow SC, Shao J, Wang H. Sample Size Calculation in Clinical Research. New York: Marcel Dekker, 2003

Examples

# NOT RUN {
Example.4.6.4<-RelativeRisk.Equivalence(0.05,0.2,2,1,0.25,0.25,.5)
Example.4.6.4

# }