U_phi_mu4zinb

Compute score statistics for ZINB model
This function takes the estimations of phi and lambda produced by the <code>phi_lambda_hat4negbin</code>
and computes the score statistics for ZINB model under the null hypothesis.

Gene‐based association tests to model count data with excessive zeros and rare variants using zero-inflated Poisson/zero-inflated negative Binomial regression framework. This method was originally described by Fan, Sun, and Li in Genetic Epidemiology 46(1):73-86 <doi:10.1002/gepi.22438>.

Xiaomin Liu

ZIM4rv

Gene‐based Association Tests of Zero‐inflated Count Phenotype
for Rare Variants

U_phi_mu4zinb function

<dl><dt>simudata</dt>
<dd>a data frame containing a phenotype named y and covariates</dd>
<dt>G_rare</dt>
<dd>a data frame containing data of rare variants with the same subject order as in simudata</dd></dl>

Arguments

U_phi_mu4zinb — U_phi_mu4zinb

<dl>

<dt>simudata</dt>
<dd>a data frame containing a phenotype named y and covariates</dd>


<dt>G_rare</dt>
<dd>a data frame containing data of rare variants with the same subject order as in simudata</dd>

</dl>

U_phi_mu4zinb: U_phi_mu4zinb

Description

Usage

Value

Arguments