abd (version 0.2-6)

LiverPreparation: Liver Preparation

Description

The unbound fraction of taurocholate for each of five concentrations of administered taurocholate.

source

Smallwood, R.H., D.J. Morgan, G.W. Mihaly, and R.A. Smallwood. 1998. Effect of a protein binding change on unbound and total plasma concentrations for drugs of intermediate hepatic extraction. Journal of Pharmacokinetics and Pharmacodynamics 16:397-411.

References

http://www.springerlink.com/content/p134310534nw8j72

Examples

data(LiverPreparation)
str(LiverPreparation)
xyplot(unbound.fraction ~ concentration, LiverPreparation)