⚠️There's a newer version (0.5.4) of this package.Take me there.

bcrm (version 0.4.7)

Bayesian Continual Reassessment Method for Phase I Dose-Escalation Trials

Description

Implements a wide variety of one and two-parameter Bayesian CRM designs. The program can run interactively, allowing the user to enter outcomes after each cohort has been recruited, or via simulation to assess operating characteristics.

Copy Link

Version

Install

install.packages('bcrm')

Monthly Downloads

381

Version

0.4.7

License

GPL (>= 2)

Maintainer

Michael Sweeting

Last Published

January 28th, 2018

Functions in bcrm (0.4.7)

plot.bcrm

Plot the estimated dose-toxicity curve

plot.bcrm.sim

Plot the operating characteristics from the simulated trials

find.x

Obtain samples from the maximum tolerated dose (MTD) distribution.

getprior

Samples from the specified prior distribution.

print.bcrm

Print information regarding a trial conducted using the Bayesian continuous reassessment method

print.threep3

Print information regarding the operating characteristics of a standard 3+3 design

plot.threep3

Plot the operating characteristics from a standard 3+3 trial

Posterior

Calculate posterior distribution of CRM model parameter(s)

bcrm-package

Bayesian Continual Reassessment Method for Phase I Dose-Escalation Trials

bcrm

Bayesian Continual Reassessment Method for Phase I Dose-Escalation Trials

threep3

Calculate all possible trial pathways for the standard 3+3 design, together with their probability of occurring