Batch effects are removed using the means of the batches.
Usage
mean_centering(Y, b)
Arguments
Y
A matrix with $n$ rows and $g$ columns, where $n$ is the number of objects and $g$
is the number of variables. In the case of gene expression data, columns correspond
to genes (probe sets) and rows to samples.
b
A vector of class factor with the element in position $i$ ($i=1,\ldots,n$) representing
the batch from which observation $i$ belongs to.
Value
A matrix of adjusted data with $n$ rows and $g$ columns.