Learn R Programming

bioOED (version 0.2.1)

Sensitivity Analysis and Optimum Experiment Design for Microbial Inactivation

Description

Extends the bioinactivation package with functions for Sensitivity Analysis and Optimum Experiment Design.

Copy Link

Version

Install

install.packages('bioOED')

Monthly Downloads

25

Version

0.2.1

License

GPL-3

Maintainer

Alberto Garre

Last Published

August 7th, 2019

Functions in bioOED (0.2.1)

inactivation_sens_handler

Handler for the calculation of sensitivities of inactivation models
plot.IsoSensitivities

Plotting of IsoSensitivities objects
calculate_pars_correlation

Correlation Between Model Parameters Sensitivities
sensitivities_Mafart

Local sensitivities of the Mafart model
sensitivities_Bigelow

Local sensitivities of the Bigelow model
calculate_isothermal_FIM

Fisher Information Matrix for isothermal experiments
calculate_FIM

Calculation of Fisher Information Matrix
criterium_D

D Optimality Criterium
isothermal_sensitivities

Local sensitivites of isothermal microbial inactivation
detFIM

Objective function for D-optimal OED
objective_D

Objective Function for the D Criterium
criterium_D_iso

Objective function for D-optimal OED with detection limit
criterium_modE

Modified-E Optimality Criterium
isothermal_OED

Optimal Experiment Design of isothermal inactivation
detection_peleg

Detection limit of the Peleg model
get_isothermal_correlation

Parameter correlation for isothermal inactivation experiments
sensitivities_Peleg

Local sensitivities of the Peleg model
objective_D_penalty

Objective Function for the D Criterium with Penalty
objective_Emod

Objective Function for the modified-E Criterium
get_detection

Calculate detection limit
sensitivity_inactivation

Local sensitivities of microbial inactivation
inactivation_OED

Optimum Experimental Design of Microbial Inactivation
isothermal_OED_limit

OED of isothermal microbial inactivation with detection limit
optimize_refTemp

Optimization of the Reference Temperature
objective_Emod_penalty

Objective Function for the modified-E Criterium with Penalty
plot.OEDinactivation

Plot of OEDinactivation
plot.OEDisothermal

Plot of OEDisothermal object
criterium_Amod_iso

Objective function for A modified-optimal OED with detection limit
criterium_A_iso

Objective function for A-optimal OED with detection limit
detection_bigelow

Detection limit of the Bigelow model
detection_mafart

Detection limit of the Mafart model
plot.parCorrelation

Correlation Plot of Parameter Sensitivities
refTemp_optim_handler

Hanlder for the Optimization of Reference Temperature
calculate_limit

"Detection" limit for each model
criterium_E_iso

Objective function for E-optimal OED with detection limit
criterium_Emod_iso

Objective function for E modified-optimal OED with detection limit
inactivation_OED_penalty

Optimum Experimental Design of Microbial Inactivation with Penalty
penalty_function

Penalty Function for OED