bioOED (version 0.2.1)

detFIM: Objective function for D-optimal OED

Description

Objective function for D-optimal OED

Usage

detFIM(x, model, pars)

Arguments

x

a numeric vector of length n defining the design matrix. The first n/2 elements are the time points and the last n/2 are the temperatures of these points.

model

character string defining the inactivation model to use.

pars

list defining the model parameters according to the rules defined in the bioinactivation package.

Value

Numeric value of the objective function for criterium D, which is a determinant of the FIM.

Examples

# NOT RUN {
pars <- list(temp_crit = 55,
        n = 1.5,
        k_b = 0.1)
detFIM(x = c(10,15, 20, 25), "Peleg", pars)

# }