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cinaR

Overview

cinaR is a single wrapper function for end-to-end computational analyses of bulk ATAC-seq (or RNA-seq) profiles. Starting from a consensus peak file, it outputs differentially accessible peaks, enrichment results, and provides users with various configurable visualization options. For more details, please see the preprint.

Installation

# CRAN mirror
install.packages("cinaR")

Development version

To get bug fix and use a feature from the development version:

# install.packages("devtools")
devtools::install_github("eonurk/cinaR")

Usage

For more details please go to our site from here!

Known Installation Issues

Sometimes bioconductor related packages may not be installed automatically.
Therefore, you may need to install them manually:

BiocManager::install(c("ChIPseeker", "DESeq2", "edgeR", "fgsea","GenomicRanges", "limma", "preprocessCore", "sva", "TxDb.Hsapiens.UCSC.hg38.knownGene", "TxDb.Hsapiens.UCSC.hg19.knownGene", "TxDb.Mmusculus.UCSC.mm10.knownGene"))

Contribution

You can send pull requests to make your contributions.

Author

License

  • GNU General Public License v3.0

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Version

Install

install.packages('cinaR')

Monthly Downloads

143

Version

0.2.3

License

GPL-3

Issues

Pull Requests

Stars

Forks

Maintainer

Onur Karakaslar

Last Published

May 18th, 2022

Functions in cinaR (0.2.3)

annotatePeaks

annotatePeaks
differentialAnalyses

Differential Analyses
filterConsensus

filterConsensus
heatmap_differential

heatmap_differential
pca_plot

pca_plot
normalizeConsensus

normalizeConsensus
bed

Example peaks from bone marrow of B6 mice
scale_rows

scale_rows
run_enrichment

run_enrichment
vp2008

Immune modules
heatmap_var_peaks

heatmap_var_peaks
verboseFn

verboseFn
show_comparisons

show_comparisons
grch38

Grch38
grcm38

Grcm38
HPEA

HPEA
color_values

color values
GSEA

GSEA
dot_plot

dot_plot
cinaR

cinaR
grch37

Grch37