clonotypeR (version 1.10.2)
High throughput analysis of T cell antigen receptor sequences
Description
High throughput analysis of T cell antigen receptor sequences
The genes encoding T cell receptors are created by somatic recombination,
generating an immense combination of V, (D) and J segments. Additional
processes during the recombination create extra sequence diversity between the
V an J segments. Collectively, this hyper-variable region is called the CDR3
loop.
The purpose of this package is to process and quantitatively analyse millions
of V-CDR3-J combination, called clonotypes, from multiple sequence libraries.