lymphoma

A subset of the aCGH data set taken from the reference below.

Penalized least squares regression is applied to fit
piecewise constant curves to copy number data to locate genomic
regions of constant copy number. Procedures are available for
individual segmentation of each sample, joint segmentation of
several samples and joint segmentation of the two data tracks
from SNP-arrays. Several plotting functions are available for
visualization of the data and the segmentation results.

Gro Nilsen

copynumber

Segmentation of single- and multi-track copy number data by
penalized least squares regression.

lymphoma function

Data frame containing 3091 probes with log2-ratio copy numbers for 21 samples. The first column contains the chromosome numbers, the second gives the local probe positions (in base pairs), while the subsequent columns contain the copy number measurements for the individual samples.

format

Eide et al., "Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones", Blood 116:1489-1497, 2010

lymphoma: 3K aCGH data

Description

Usage

Arguments

format

source

Examples