micma

A subset of the 244K MicMa data set containing copy number measurements for six samples on chromosome 17.

Penalized least squares regression is applied to fit
piecewise constant curves to copy number data to locate genomic
regions of constant copy number. Procedures are available for
individual segmentation of each sample, joint segmentation of
several samples and joint segmentation of the two data tracks
from SNP-arrays. Several plotting functions are available for
visualization of the data and the segmentation results.

Gro Nilsen

copynumber

Segmentation of single- and multi-track copy number data by
penalized least squares regression.

micma function

Data frame containing 7658 probes with log2-ratio copy numbers for 6 samples on chromosome 17. The first column contains the chromosome numbers, the second gives the local probe positions (in base pairs), while the subsequent columns contain the copy number measurements for the individual samples.

format

Mathiesen et al., "High resolution analysis of copy number changes in disseminated tumor cells of patients with breast cancer", Int J Cancer 131(4):E405:E415, 2011

micma: Subset of 244K aCGH data

Description

Usage

Arguments

format

source

Examples