pvalue.hub: Compuation of gene connection sigificance values in a Gene Co-expression network
Description
The function computes ths statisical significance values of gene connections in a GCN for a particular condition/trait/stress
Usage
pvalue.hub(x, beta, m, s, plot=TRUE)
Arguments
x
x is a data frame of gene expression values where rows represent genes and columns represent samples/time point under a particular condition/trait/stress.
beta
beta is a soft threshold parameter determined from the scale free property of biological networks (Gene Co-expression network).
m
m is a scalar representing sample size and is less than or equal to number of columns in x.
s
s is a scalar representing number of times each of the m samples will be resampled.
plot
plot is a character must either take logical value TRUE/FALSE representing whether the plot of the pvalues of gene connections of all genes in Gene Co-expression Network needs to be constructed or not.