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dinamic (version 1.0)

wilms.data: DNA Copy Number Data from Natrajan et al. (2006)

Description

Natrajan et al. (J. Pathology (2006) 210: 49 - 58) used array comparative genomic hybridization to obtain genome-wide DNA copy number data from 97 Wilms' tumor samples at 3288 markers. This matrix contains the DNA copy number data after applying the bias-correction procedure outlined in Bioinformatics (2011) 27(5) 678 - 685. Each row corresponds to DNA copy number from one subject at 3288 markers, while each column contains DNA copy number data for 97 subjects at one marker.

Usage

data(wilms.data)

Arguments

Format

A 97 by 3288 numeric matrix containing DNA copy number data, as described above.

References

Natrajan, R., Williams, R.D., Hing, S.N., et al., Array CGH profiling of favourable histology Wilms tumours reveals novel gains and losses associated with relapse, J. Pathology (2006) 210: 49 - 58.

Walter, V., Nobel, A.B., and Wright, F.A., DiNAMIC: a method to identify recurrent DNA copy number aberrations in tumors, Bioinformatics (2011) 27(5) 678 - 685.