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drc (version 1.5-2)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

28,339

Version

1.5-2

License

GPL (>= 2)

Maintainer

Christian Ritz

Last Published

February 15th, 2017

Functions in drc (1.5-2)

MM

Michaelis-Menten model
heartrate

Heart rate baroreflexes for rabbits
leaflength

Leaf length of barley
llogistic

The log-logistic function
W1.4

The four-parameter Weibull functions
S.alba

Potency of two herbicides
BC.5

The Brain-Cousens hormesis models
MAX

Maximum mean response
W1.3

The three-parameter Weibull functions
plot.drc

Plotting fitted curves for a 'drc' or 'mrdrc' object
LL.4

The four-parameter log-logistic function
acidiq

Acifluorfen and diquat tested on Lemna minor.
confint.drc

Confidence Intervals for model parameters
asymreg

Asymptotic regression model
mixdrc

Fitting multiple dose-response curves with random effects
earthworms

Earthworms
bread.drc

Bread and meat for the sandwich
fitted.drc

Extract fitted values from model
W1.2

The two-parameter Weibull functions
LL.5

The five-parameter log-logistic function
RScompetition

Competition between two biotypes
lettuce

Isobutylalcohol in nutrient solution in which lettuce plants were grown
G.aparine

Herbicide applied to Galium aparine
lepidium

Dose-response profile of degradation of agrochemical using lepidium
drm

Fitting dose-response models
methionine

Weight gain for different methionine sources
anova.drc

ANOVA for non-linear model fits
colFct

Collapse of levels
expdecay

Exponential decay model
beetGrowth

Example of plant growth curve from Covarelli and Onofri (1998)
coef.drc

Extract Model Coefficients
deguelin

Deguelin applied to chrysanthemum aphis
ED.drc

Estimating effective doses
drmc

Sets control arguments
multdrc

Fitting multiple dose-response curves
braincousens

The Brain-Cousens hormesis models
O.mykiss

Test data from a 21 day fish test
mecter

Mechlorprop and terbythylazine tested on Lemna minor
finney71

Example from Finney (1971)
isobole

Creating isobolograms
mixture

Fitting mixture models
compParm

Comparison of parameters
PR

Expected or predicted response
daphnids

Daphnia test
glymet

Glyphosate and metsulfuron-methyl tested on algae.
logLik.drc

Extracting the log likelihood
gompertzd

The derivative of the Gompertz function
SI

Comparing selectivity indices across curves
diagnostics

Information on estimation
getMeanFunctions

Display available dose-response models
CRS.4a

The Cedergreen-Ritz-Streibig model
gompGrowth

Gompertz growth models
cedergreen

The Cedergreen-Ritz-Streibig model
LL.3

The three-parameter log-logistic function
auxins

Effect of technical grade and commerecially formulated auxin herbicides
boxcox.drc

Transform-both-sides Box-Cox transformation
predict.drc

Prediction
CRS.5a

The Cedergreen-Ritz-Streibig model
baro5

The modified baro5 function
mdControl

Sets control arguments
comped

Comparison of effective dose values
logistic

The logistic (Boltzmann) model
print.summary.drc

Printing summary of non-linear model fits
vinclozolin

Vinclozolin from AR in vitro assay
print.drc

Printing key features
weibull1

The Weibull functions
rdrm

Simulating a dose-response curve
update.drc

Updating and re-fitting a model
spinach

Inhibition of photosynthesis
secalonic

Root length
mrdrm

Model-robust dose-response modelling
LL.2

The two-parameter log-logistic function
richards

Richards model
residuals.drc

Extracting residuals from model
simDR

Simulating ED values under various scenarios
mselect

Model selection
ryegrass

Effect of ferulic acid on growth of ryegrass
summary.drc

Summarising non-linear model fits
terbuthylazin

The effect of terbuthylazin on growth rate
nasturtium

Dose-response profile of degradation of agrochemical using nasturtium
searchdrc

Searching through a range of initial parameter values to obtain convergence
plotraw

Plotting raw dose response data.
vcov.drc

Calculating Variance-Covariance Matrix for objects of class 'drc'