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drc (version 1.7-0)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

58,200

Version

1.7-0

License

GPL (>= 2)

Homepage

http://www.r-project.org

Maintainer

Christian Ritz

Last Published

June 8th, 2009

Functions in drc (1.7-0)

Effect of an effluent on the growth of mysid shrimp

Competition between two biotypes

Sets control arguments

Effect of technical grade and commercially formulated auxin herbicides

Confidence Intervals for model parameters

Comparing selectivity indices across curves

S.capricornutum

Effect of cadmium on growth of green alga

Maximum mean response

The derivative of the Gompertz function

Model-robust dose-response modelling

Glyphosate and metsulfuron-methyl tested on algae.

Earthworm toxicity test

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis

Leaf length of barley

The Brain-Cousens hormesis models

print.summary.drc

Printing summary of non-linear model fits

Fitting multiple dose-response curves with random effects

Information on estimation

Log-normal dose-response model

Fractional polynomial-logistic dose-response models

Effect of sodium pentachlorophenate on growth of fathead minnow

Vinclozolin from AR in vitro assay

ANOVA for non-linear model fits

Effect of ferulic acid on growth of ryegrass

Test data from a 21 day fish test

Calculating yield loss parameters

Summarising non-linear model fits

Example of plant growth curve from Covarelli and Onofri (1998)

Mechlorprop and terbythylazine tested on Lemna minor

Mean function for the Gompertz dose-response or growth curve

Inhibition of photosynthesis

Fitting dose-response models

Weight gain for different methionine sources

Model selection

Mortality of tobacco budworms

The Cedergreen-Ritz-Streibig model

Extracting the log likelihood

Gompertz growth models

Extracting residuals from model

The log-logistic function

Volume of algae as function of increasing concentrations of a herbicide

Dose-response profile of degradation of agrochemical using nasturtium

Heart rate baroreflexes for rabbits

Extract fitted values from model

Acifluorfen and diquat tested on Lemna minor.

The four-parameter log-logistic function

Isobutylalcohol in nutrient solution in which lettuce plants were grown

Showing starting values used

Asymptotic regression model

The Cedergreen-Ritz-Streibig model

The logistic model

Comparison of parameters

Dose-response profile of degradation of agrochemical using lepidium

The effect of terbuthylazin on growth rate

The Brain-Cousens hormesis models

Estimating effective doses

Exponential decay model

The three-parameter log-logistic function

Michaelis-Menten model

Comparison of effective dose values

Printing key features

Deguelin applied to chrysanthemum aphis

The three-parameter Weibull functions

Creating isobolograms

Searching through a range of initial parameter values to obtain convergence

Plotting fitted curves for a 'drc' or 'mrdrc' object

Herbicide applied to Galium aparine

The four-parameter Weibull functions

The two-parameter Weibull functions

Transform-both-sides Box-Cox transformation

Checking the model fot

Potency of two herbicides

Bread and meat for the sandwich

Estimation of ED values using model-averaging

Simulating a dose-response curve

Weibull model functions

The modified baro5 function

The five-parameter log-logistic function

getMeanFunctions

Display available dose-response models

Example from Finney (1971)

Expected or predicted response

Extract Model Coefficients

Simulating ED values under various scenarios

Updating and re-fitting a model

Continuous data from ECVAM

The two-parameter log-logistic function

Fitting mixture models

Calculating variance-covariance matrix for objects of class 'drc'