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drc (version 1.7-2)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

58,200

Version

1.7-2

License

GPL (>= 2)

Homepage

http://www.r-project.org

Maintainer

Christian Ritz

Last Published

July 18th, 2009

Functions in drc (1.7-2)

Effect of an effluent on the growth of mysid shrimp

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis

Fitting mixture models

Asymptotic regression model

Acifluorfen and diquat tested on Lemna minor.

The Cedergreen-Ritz-Streibig model

Exponential decay model

Comparing selectivity indices across curves

Deguelin applied to chrysanthemum aphis

Weibull model functions

Effect of sodium pentachlorophenate on growth of fathead minnow

S.capricornutum

Effect of cadmium on growth of green alga

Leaf length of barley

Estimation of ED values using model-averaging

Effect of technical grade and commercially formulated auxin herbicides

Simulating a dose-response curve

Estimating effective doses

The log-logistic function

Fractional polynomial-logistic dose-response models

Michaelis-Menten model

Sets control arguments

Extract fitted values from model

The modified baro5 function

The two-parameter Weibull functions

Checking the model fot

Earthworm toxicity test

Log-normal dose-response model

Mizon-Richard test for dose-response models

Model-robust dose-response modelling

Mechlorprop and terbythylazine tested on Lemna minor

Mortality of tobacco budworms

Heart rate baroreflexes for rabbits

Isobutylalcohol in nutrient solution in which lettuce plants were grown

Model selection

Gompertz growth models

Effect of erythromycin on mixed sewage microorganisms

Expected or predicted response

The five-parameter log-logistic function

Potency of two herbicides

The two-parameter log-logistic function

Dose-response profile of degradation of agrochemical using lepidium

Test data from a 21 day fish test

The four-parameter Weibull functions

The Cedergreen-Ritz-Streibig model

Lack-of-fit test for the mean structure based on cumulated residuals

The effect of terbuthylazin on growth rate

Herbicide applied to Galium aparine

Confidence Intervals for model parameters

Summarising non-linear model fits

Extract Model Coefficients

Neill's lack-of-fit test for dose-response models

Bread and meat for the sandwich

The Brain-Cousens hormesis models

Plotting fitted curves for a 'drc' or 'mrdrc' object

The Brain-Cousens hormesis models

Example from Finney (1971)

Calculating yield loss parameters

The three-parameter Weibull functions

Maximum mean response

ANOVA for non-linear model fits

Information on estimation

Fitting dose-response models

Weight gain for different methionine sources

Searching through a range of initial parameter values to obtain convergence

Comparison of parameters

The derivative of the Gompertz function

Extracting residuals from model

Printing key features

Vinclozolin from AR in vitro assay

The three-parameter log-logistic function

getMeanFunctions

Display available dose-response models

Transform-both-sides Box-Cox transformation

Continuous data from ECVAM

Inhibition of photosynthesis

Calculating variance-covariance matrix for objects of class 'drc'

Competition between two biotypes

Glyphosate and metsulfuron-methyl tested on algae.

Extracting the log likelihood

Showing starting values used

Dose-response profile of degradation of agrochemical using nasturtium

Example of plant growth curve from Covarelli and Onofri (1998)

The logistic model

Effect of ferulic acid on growth of ryegrass

Volume of algae as function of increasing concentrations of a herbicide

Mean function for the Gompertz dose-response or growth curve

Updating and re-fitting a model

The four-parameter log-logistic function

Comparison of effective dose values

Creating isobolograms

Fitting multiple dose-response curves with random effects

Simulating ED values under various scenarios

print.summary.drc

Printing summary of non-linear model fits