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drc (version 1.7-7)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

58,200

Version

1.7-7

License

GPL (>= 2)

Homepage

http://www.r-project.org

Maintainer

Christian Ritz

Last Published

September 3rd, 2009

Functions in drc (1.7-7)

Exponential decay model

Gompertz growth models

Fractional polynomial-logistic dose-response models

Acifluorfen and diquat tested on Lemna minor.

The Brain-Cousens hormesis models

Asymptotic regression model

The derivative of the Gompertz function

Extract Model Coefficients

The Brain-Cousens hormesis models

Searching through a range of initial parameter values to obtain convergence

S.capricornutum

Effect of cadmium on growth of green alga

The four-parameter log-logistic function

The four-parameter Weibull functions

Glyphosate and metsulfuron-methyl tested on algae.

Leaf length of barley

Model-robust dose-response modelling

Mortality of tobacco budworms

Creating isobolograms

Potency of two herbicides

The log-logistic function

Sets control arguments

Effect of sodium pentachlorophenate on growth of fathead minnow

Printing key features

Root length measurements

Deguelin applied to chrysanthemum aphis

Inhibition of photosynthesis

The Cedergreen-Ritz-Streibig model

Dose-response profile of degradation of agrochemical using lepidium

Log-normal dose-response model

Extracting residuals from model

The modified baro5 function

Lack-of-fit test for the mean structure based on cumulated residuals

Neill's lack-of-fit test for dose-response models

ANOVA for dose-response model fits

The Cedergreen-Ritz-Streibig model

Isobutylalcohol in nutrient solution in which lettuce plants were grown

Information on estimation

Calculating variance-covariance matrix for objects of class 'drc'

The effect of terbuthylazin on growth rate

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis

Effect of technical grade and commercially formulated auxin herbicides

Weight gain for different methionine sources

Mean function for the Gompertz dose-response or growth curve

Showing starting values used

Calculating yield loss parameters

Volume of algae as function of increasing concentrations of a herbicide

Comparison of parameters

Earthworm toxicity test

Continuous data from ECVAM

Extract fitted values from model

Weibull model functions

Example from Finney (1971)

Michaelis-Menten model

Expected or predicted response

Model selection

Estimating effective doses

Fitting dose-response models

Two-phase dose-response model

The logistic model

Effect of ferulic acid on growth of ryegrass

Bread and meat for the sandwich

Dose-response profile of degradation of agrochemical using nasturtium

Test data from a 21 day fish test

The three-parameter log-logistic function

Competition between two biotypes

The three-parameter Weibull functions

Confidence Intervals for model parameters

The two-parameter log-logistic function

Fitting multiple dose-response curves with random effects

Heart rate baroreflexes for rabbits

The five-parameter log-logistic function

Example of plant growth curve from Covarelli and Onofri (1998)

Extracting the log likelihood

Summarising non-linear model fits

getMeanFunctions

Display available dose-response models

Vinclozolin from AR in vitro assay

The two-parameter Weibull functions

Maximum mean response

Mechlorprop and terbythylazine tested on Lemna minor

Plotting fitted curves for a 'drc' or 'mrdrc' object

Simulating ED values under various scenarios

print.summary.drc

Printing summary of non-linear model fits

Simulating a dose-response curve

Estimation of ED values using model-averaging

Updating and re-fitting a model

Herbicide applied to Galium aparine

Checking the model fot

Effect of erythromycin on mixed sewage microorganisms

Comparing selectivity indices across curves

Transform-both-sides Box-Cox transformation

Fitting mixture models

Mizon-Richard test for dose-response models

Effect of an effluent on the growth of mysid shrimp