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drc (version 1.8-1)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

58,200

Version

1.8-1

License

GPL (>= 2)

Maintainer

Christian Ritz

Last Published

January 12th, 2010

Functions in drc (1.8-1)

lepidium

Dose-response profile of degradation of agrochemical using lepidium
S.capricornutum

Effect of cadmium on growth of green alga
MM

Michaelis-Menten model
braincousens

The Brain-Cousens hormesis models
LL.2

The two-parameter log-logistic function
acidiq

Acifluorfen and diquat tested on Lemna minor.
boxcox.drc

Transform-both-sides Box-Cox transformation
H.virescens

Mortality of tobacco budworms
LL.4

The four-parameter log-logistic function
bread.drc

Bread and meat for the sandwich
NEC

Dose-response model for estimation of no effect concentration (NEC).
ED.drc

Estimating effective doses
lin.test

Lack-of-fit test for the mean structure based on cumulated residuals
anova.drc

ANOVA for dose-response model fits
O.mykiss

Test data from a 21 day fish test
SI

Comparing selectivity indices across curves
coef.drc

Extract Model Coefficients
drm

Fitting dose-response models
modelFit

Checking the model fot
print.drc

Printing key features
logistic

The logistic model
nasturtium

Dose-response profile of degradation of agrochemical using nasturtium
ryegrass

Effect of ferulic acid on growth of ryegrass
mr.test

Mizon-Richard test for dose-response models
W1.4

The four-parameter Weibull functions
S.alba

Potency of two herbicides
confint.drc

Confidence Intervals for model parameters
auxins

Effect of technical grade and commercially formulated auxin herbicides
predict.drc

Prediction
beetGrowth

Example of plant growth curve from Covarelli and Onofri (1998)
fitted.drc

Extract fitted values from model
deguelin

Deguelin applied to chrysanthemum aphis
vinclozolin

Vinclozolin from AR in vitro assay
ecvam

Continuous data from ECVAM
EXD

Exponential decay model
CRS.5a

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
BC.5

The Brain-Cousens hormesis models
M.bahia

Effect of an effluent on the growth of mysid shrimp
gompertz

Mean function for the Gompertz dose-response or growth curve
gompGrowth

Gompertz growth models
W1.3

The three-parameter Weibull functions
earthworms

Earthworm toxicity test
yieldLoss

Calculating yield loss parameters
baro5

The modified baro5 function
diagnostics

Information on estimation
compParm

Comparison of parameters
finney71

Example from Finney (1971)
etmotc

Effect of erythromycin on mixed sewage microorganisms
fplogistic

Fractional polynomial-logistic dose-response models
P.promelas

Effect of sodium pentachlorophenate on growth of fathead minnow
MAX

Maximum mean response
drmc

Sets control arguments
PR

Expected or predicted response
getMeanFunctions

Display available dose-response models
plot.drc

Plotting fitted curves for a 'drc' or 'mrdrc' object
lettuce

Isobutylalcohol in nutrient solution in which lettuce plants were grown
llogistic

The log-logistic function
mselect

Model selection
maED

Estimation of ED values using model-averaging
gompertzd

The derivative of the Gompertz function
mixdrc

Fitting multiple dose-response curves with random effects
mixture

Fitting mixture models
neill.test

Neill's lack-of-fit test for dose-response models
mrdrm

Model-robust dose-response modelling
print.summary.drc

Printing summary of non-linear model fits
terbuthylazin

The effect of terbuthylazin on growth rate
summary.drc

Summarising non-linear model fits
mecter

Mechlorprop and terbythylazine tested on Lemna minor
residuals.drc

Extracting residuals from model
searchdrc

Searching through a range of initial parameter values to obtain convergence
weibull1

Weibull model functions
simDR

Simulating ED values under various scenarios
vcov.drc

Calculating variance-covariance matrix for objects of class 'drc'
methionine

Weight gain for different methionine sources
twophase

Two-phase dose-response model
rdrm

Simulating a dose-response curve
CRS.4a

The Cedergreen-Ritz-Streibig model
AR

Asymptotic regression model
LL.3

The three-parameter log-logistic function
LL.5

The five-parameter log-logistic function
RScompetition

Competition between two biotypes
leaflength

Leaf length of barley
algae

Volume of algae as function of increasing concentrations of a herbicide
daphnids

Daphnia test
getInitial

Showing starting values used
glymet

Glyphosate and metsulfuron-methyl tested on algae.
logLik.drc

Extracting the log likelihood
spinach

Inhibition of photosynthesis
isobole

Creating isobolograms
secalonic

Root length measurements
update.drc

Updating and re-fitting a model
W1.2

The two-parameter Weibull functions
cedergreen

The Cedergreen-Ritz-Streibig model
G.aparine

Herbicide applied to Galium aparine
heartrate

Heart rate baroreflexes for rabbits
lnormal

Log-normal dose-response model