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drc (version 1.9-0)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

28,339

Version

1.9-0

License

GPL (>= 2)

Homepage

http://www.r-project.org

Maintainer

Christian Ritz

Last Published

April 23rd, 2010

Functions in drc (1.9-0)

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis

Acifluorfen and diquat tested on Lemna minor.

Dose-response model for estimation of no effect concentration (NEC).

The three-parameter Weibull functions

The four-parameter log-logistic function

The Brain-Cousens hormesis models

Comparison of effective dose values

Maximum mean response

Test data from a 21 day fish test

Estimating effective doses

Heart rate baroreflexes for rabbits

Leaf length of barley

Effect of technical grade and commercially formulated auxin herbicides

Fitting multiple dose-response curves with random effects

Exponential decay model

Confidence Intervals for model parameters

Effect of an effluent on the growth of mysid shrimp

The two-parameter log-logistic function

Dose-response profile of degradation of agrochemical using lepidium

The Brain-Cousens hormesis models

Showing starting values used

The five-parameter log-logistic function

Bayesian Information Criterion for dose-response models

Fitting mixture models

Checking the model fot

Deguelin applied to chrysanthemum aphis

Asymptotic regression model

Example of plant growth curve from Covarelli and Onofri (1998)

Weight gain for different methionine sources

Effect of sodium pentachlorophenate on growth of fathead minnow

Inhibition of photosynthesis

Competition between two biotypes

Calculating yield loss parameters

S.capricornutum

Effect of cadmium on growth of green alga

Extracting residuals from model

Printing key features

Root length measurements

Expected or predicted response

Summarising non-linear model fits

The three-parameter log-logistic function

The modified baro5 function

Fractional polynomial-logistic dose-response models

Two-phase dose-response model

Fitting dose-response models

The derivative of the Gompertz function

Herbicide applied to Galium aparine

Isobutylalcohol in nutrient solution in which lettuce plants were grown

Continuous data from ECVAM

print.summary.drc

Printing summary of non-linear model fits

Searching through a range of initial parameter values to obtain convergence

Simulating ED values under various scenarios

Extract Model Coefficients

Estimation of ED values using model-averaging

Vinclozolin from AR in vitro assay

Creating isobolograms

The logistic model

Neill's lack-of-fit test for dose-response models

Model-robust dose-response modelling

Model selection

The log-logistic function

The effect of terbuthylazin on growth rate

Glyphosate and metsulfuron-methyl tested on algae.

Information on estimation

The Cedergreen-Ritz-Streibig model

Log-normal dose-response model

Effect of ferulic acid on growth of ryegrass

Dose-response profile of degradation of agrochemical using nasturtium

Weibull model functions

Simulating a dose-response curve

Sets control arguments

Mortality of tobacco budworms

Mechlorprop and terbythylazine tested on Lemna minor

Transform-both-sides Box-Cox transformation

Effect of erythromycin on mixed sewage microorganisms

Extracting the log likelihood

Volume of algae as function of increasing concentrations of a herbicide

Updating and re-fitting a model

The Cedergreen-Ritz-Streibig model

Extract fitted values from model

Comparing selectivity indices across curves

Bayesian Information Criterion for dose-response models

Potency of two herbicides

The two-parameter Weibull functions

getMeanFunctions

Display available dose-response models

Gompertz growth models

Example from Finney (1971)

Mizon-Richard test for dose-response models

Earthworm toxicity test

ANOVA for dose-response model fits

Michaelis-Menten model

The four-parameter Weibull functions

Bread and meat for the sandwich

Mean function for the Gompertz dose-response or growth curve

Lack-of-fit test for the mean structure based on cumulated residuals

Comparison of parameters

Calculating variance-covariance matrix for objects of class 'drc'

Plotting fitted curves for a 'drc' or 'mrdrc' object

Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction