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drc (version 1.9-3)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

28,339

Version

1.9-3

License

GPL (>= 2)

Homepage

http://www.r-project.org

Maintainer

Christian Ritz

Last Published

May 31st, 2010

Functions in drc (1.9-3)

Exponential decay model

Effect of an effluent on the growth of mysid shrimp

Fitting dose-response models

Michaelis-Menten model

Bayesian Information Criterion for dose-response models

The four-parameter log-logistic function

Leaf length of barley

Volume of algae as function of increasing concentrations of a herbicide

Mortality of tobacco budworms

Deguelin applied to chrysanthemum aphis

Effect of sodium pentachlorophenate on growth of fathead minnow

Example from Finney (1971)

The three-parameter Weibull functions

Dose-response model for estimation of no effect concentration (NEC).

Comparison of effective dose values

Glyphosate and metsulfuron-methyl tested on algae.

Herbicide applied to Galium aparine

Maximum mean response

Effect of erythromycin on mixed sewage microorganisms

getMeanFunctions

Display available dose-response models

Mechlorprop and terbythylazine tested on Lemna minor

The effect of terbuthylazin on growth rate

Fractional polynomial-logistic dose-response models

Neill's lack-of-fit test for dose-response models

The Brain-Cousens hormesis models

Calculating variance-covariance matrix for objects of class 'drc'

print.summary.drc

Printing summary of non-linear model fits

Extract fitted values from model

Effect of technical grade and commercially formulated auxin herbicides

The two-parameter log-logistic function

Root length measurements

Bayesian Information Criterion for dose-response models

Heart rate baroreflexes for rabbits

The logistic model

Sets control arguments

Extract Model Coefficients

Weight gain for different methionine sources

The derivative of the Gompertz function

Vinclozolin from AR in vitro assay

The two-parameter Weibull functions

Summarising non-linear model fits

Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction

Simulating a dose-response curve

Fitting mixture models

The Cedergreen-Ritz-Streibig model

Mizon-Richard test for dose-response models

Weibull model functions

Two-phase dose-response model

Printing key features

The Brain-Cousens hormesis models

Showing starting values used

Gompertz growth models

The four-parameter Weibull functions

The Cedergreen-Ritz-Streibig model

Updating and re-fitting a model

Extracting the log likelihood

Estimating effective doses

Earthworm toxicity test

Transform-both-sides Box-Cox transformation

Comparison of parameters

Log-normal dose-response model

Competition between two biotypes

Creating isobolograms

Extracting residuals from model

Comparing selectivity indices across curves

S.capricornutum

Effect of cadmium on growth of green alga

Dose-response profile of degradation of agrochemical using nasturtium

Potency of two herbicides

Isobutylalcohol in nutrient solution in which lettuce plants were grown

Simulating ED values under various scenarios

Calculating yield loss parameters

Model selection

Plotting fitted curves for a 'drc' or 'mrdrc' object

Effect of ferulic acid on growth of ryegrass

Mean function for the Gompertz dose-response or growth curve

The log-logistic function

Estimation of ED values using model-averaging

Asymptotic regression model

Expected or predicted response

Acifluorfen and diquat tested on Lemna minor.

ANOVA for dose-response model fits

Example of plant growth curve from Covarelli and Onofri (1998)

Lack-of-fit test for the mean structure based on cumulated residuals

Confidence Intervals for model parameters

Model-robust dose-response modelling

Checking the model fot

Inhibition of photosynthesis

Searching through a range of initial parameter values to obtain convergence

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis

Test data from a 21 day fish test

The three-parameter log-logistic function

The five-parameter log-logistic function

The modified baro5 function

Bread and meat for the sandwich

Information on estimation

Dose-response profile of degradation of agrochemical using lepidium