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drc (version 2.1-4)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

58,200

Version

2.1-4

License

GPL-2

Maintainer

Christian Ritz

Last Published

April 10th, 2011

Functions in drc (2.1-4)

H.virescens

Mortality of tobacco budworms
MM

Michaelis-Menten model
braincousens

The Brain-Cousens hormesis models
O.mykiss

Test data from a 21 day fish test
leaflength

Leaf length of barley
algae

Volume of algae as function of increasing concentrations of a herbicide
fplogistic

Fractional polynomial-logistic dose-response models
NEC

Dose-response model for estimation of no effect concentration (NEC).
diagnostics

Information on estimation
fitted.drc

Extract fitted values from model
ED.drc

Estimating effective doses
getInitial

Showing starting values used
logLik.drc

Extracting the log likelihood
lepidium

Dose-response profile of degradation of agrochemical using lepidium
etmotc

Effect of erythromycin on mixed sewage microorganisms
twophase

Two-phase dose-response model
getMeanFunctions

Display available dose-response models
daphnids

Daphnia test
mrdrm

Model-robust dose-response modelling
RScompetition

Competition between two biotypes
mr.test

Mizon-Richard test for dose-response models
rdrm

Simulating a dose-response curve
MAX

Maximum mean response
G.aparine

Herbicide applied to Galium aparine
CRS.5a

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
lin.test

Lack-of-fit test for the mean structure based on cumulated residuals
W1.4

The four-parameter Weibull functions
M.bahia

Effect of an effluent on the growth of mysid shrimp
boxcox.drc

Transform-both-sides Box-Cox transformation
yieldLoss

Calculating yield loss parameters
beetGrowth

Example of plant growth curve from Covarelli and Onofri (1998)
mecter

Mechlorprop and terbythylazine tested on Lemna minor
CRS.4a

The Cedergreen-Ritz-Streibig model
LL.2

The two-parameter log-logistic function
anova.drc

ANOVA for dose-response model fits
SI

Comparing selectivity indices across curves
PR

Expected or predicted response
simDR

Simulating ED values under various scenarios
llogistic

The log-logistic function
lettuce

Isobutylalcohol in nutrient solution in which lettuce plants were grown
comped

Comparison of effective dose values
coef.drc

Extract Model Coefficients
confint.drc

Confidence Intervals for model parameters
drmc

Sets control arguments
drm

Fitting dose-response models
S.alba

Potency of two herbicides
auxins

Effect of technical grade and commercially formulated auxin herbicides
cedergreen

The Cedergreen-Ritz-Streibig model
ryegrass

Effect of ferulic acid on growth of ryegrass
glymet

Glyphosate and metsulfuron-methyl tested on algae.
ursa

Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
bread.drc

Bread and meat for the sandwich
finney71

Example from Finney (1971)
gompertzd

The derivative of the Gompertz function
terbuthylazin

The effect of terbuthylazin on growth rate
print.drc

Printing key features
gompertz

Mean function for the Gompertz dose-response or growth curve
deguelin

Deguelin applied to chrysanthemum aphis
S.capricornutum

Effect of cadmium on growth of green alga
isobole

Creating isobolograms
spinach

Inhibition of photosynthesis
W1.3

The three-parameter Weibull functions
mselect

Model selection
maED

Estimation of ED values using model-averaging
gompGrowth

Gompertz growth models
predict.drc

Prediction
neill.test

Neill's lack-of-fit test for dose-response models
plot.drc

Plotting fitted curves for a 'drc' or 'mrdrc' object
LL.3

The three-parameter log-logistic function
EXD

Exponential decay model
lnormal

Log-normal dose-response model
LL.5

The five-parameter log-logistic function
heartrate

Heart rate baroreflexes for rabbits
print.summary.drc

Printing summary of non-linear model fits
acidiq

Acifluorfen and diquat tested on Lemna minor.
compParm

Comparison of parameters
vcov.drc

Calculating variance-covariance matrix for objects of class 'drc'
residuals.drc

Extracting residuals from model
nasturtium

Dose-response profile of degradation of agrochemical using nasturtium
methionine

Weight gain for different methionine sources
vinclozolin

Vinclozolin from AR in vitro assay
summary.drc

Summarising non-linear model fits
secalonic

Root length measurements
BC.5

The Brain-Cousens hormesis models
AR

Asymptotic regression model
LL.4

The four-parameter log-logistic function
P.promelas

Effect of sodium pentachlorophenate on growth of fathead minnow
logistic

The logistic model
baro5

The modified baro5 function
mixture

Fitting mixture models
update.drc

Updating and re-fitting a model
modelFit

Checking the model fot
weibull1

Weibull model functions
searchdrc

Searching through a range of initial parameter values to obtain convergence
earthworms

Earthworm toxicity test
W1.2

The two-parameter Weibull functions