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drc (version 2.2-1)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

58,200

Version

2.2-1

License

GPL-2

Homepage

http://www.r-project.org

Maintainer

Christian Ritz

Last Published

September 20th, 2011

Functions in drc (2.2-1)

The Brain-Cousens hormesis models

Heart rate baroreflexes for rabbits

Michaelis-Menten model

The four-parameter Weibull functions

Comparison of effective dose values

ANOVA for dose-response model fits

Maximum mean response

The four-parameter log-logistic function

Isobutylalcohol in nutrient solution in which lettuce plants were grown

Deguelin applied to chrysanthemum aphis

Example of plant growth curve from Covarelli and Onofri (1998)

Fractional polynomial-logistic dose-response models

Showing starting values used

Printing key features

Extracting residuals from model

Creating isobolograms

Fitting mixture models

The effect of terbuthylazin on growth rate

Summarising non-linear model fits

Calculating yield loss parameters

Mortality of tobacco budworms

Effect of an effluent on the growth of mysid shrimp

The two-parameter Weibull functions

Herbicide applied to Galium aparine

Test data from a 21 day fish test

Exponential decay model

Earthworm toxicity test

The three-parameter Weibull functions

Asymptotic regression model

Bread and meat for the sandwich

Effect of technical grade and commercially formulated auxin herbicides

Example from Finney (1971)

Estimating effective doses

The Brain-Cousens hormesis models

Expected or predicted response

Transform-both-sides Box-Cox transformation

The three-parameter log-logistic function

getMeanFunctions

Display available dose-response models

Fitting dose-response models

Vinclozolin from AR in vitro assay

Mizon-Richard test for dose-response models

Leaf length of barley

Sets control arguments

Log-normal dose-response model

Effect of erythromycin on mixed sewage microorganisms

The Cedergreen-Ritz-Streibig model

S.capricornutum

Effect of cadmium on growth of green alga

Potency of two herbicides

Lack-of-fit test for the mean structure based on cumulated residuals

Extracting the log likelihood

Model-robust dose-response modelling

Simulating a dose-response curve

Gompertz growth models

Mechlorprop and terbythylazine tested on Lemna minor

The logistic model

Dose-response model for estimation of no effect concentration (NEC).

Confidence Intervals for model parameters

The modified baro5 function

Weight gain for different methionine sources

Extract Model Coefficients

Information on estimation

Effect of ferulic acid on growth of ryegrass

Searching through a range of initial parameter values to obtain convergence

print.summary.drc

Printing summary of non-linear model fits

Weibull model functions

Estimation of ED values using model-averaging

Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction

The Cedergreen-Ritz-Streibig model

Effect of sodium pentachlorophenate on growth of fathead minnow

Glyphosate and metsulfuron-methyl tested on algae.

Acifluorfen and diquat tested on Lemna minor.

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis

Comparing selectivity indices across curves

The log-logistic function

Competition between two biotypes

Simulating ED values under various scenarios

Volume of algae as function of increasing concentrations of a herbicide

Root length measurements

Comparison of parameters

Extract fitted values from model

Calculating variance-covariance matrix for objects of class 'drc'

Mean function for the Gompertz dose-response or growth curve

Checking the model fot

Plotting fitted curves for a 'drc' or 'mrdrc' object

Neill's lack-of-fit test for dose-response models

Inhibition of photosynthesis

Model selection

The five-parameter log-logistic function

The two-parameter log-logistic function

Dose-response profile of degradation of agrochemical using lepidium

The derivative of the Gompertz function

Two-phase dose-response model

Updating and re-fitting a model

Dose-response profile of degradation of agrochemical using nasturtium