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drc (version 2.2-9)

Analysis of dose-response curves

Description

Analysis of one or multiple curves with focus on concentration-response, dose-response and time-response curves used, for example in biology, environmental sciences, medicine, pharmacology, toxicology.

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Version

Install

install.packages('drc')

Monthly Downloads

58,200

Version

2.2-9

License

GPL-2

Homepage

http://www.r-project.org

Maintainer

Christian Ritz

Last Published

June 10th, 2012

Functions in drc (2.2-9)

Confidence Intervals for model parameters

Comparison of parameters

Information on estimation

The logistic model

Hormesis in lettuce plants

Fitting dose-response models

Example from Finney (1971)

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis

Effect of sodium pentachlorophenate on growth of fathead minnow

Dose-response profile of degradation of agrochemical using lepidium

Root length measurements

Comparing selectivity indices across curves

Weight gain for different methionine sources

Extract Model Coefficients

Calculating variance-covariance matrix for objects of class 'drc'

Comparison of effective dose values

Extracting the log likelihood

Neill's lack-of-fit test for dose-response models

The Cedergreen-Ritz-Streibig model

Vinclozolin from AR in vitro assay

Searching through a range of initial parameter values to obtain convergence

The three-parameter Weibull functions

ANOVA for dose-response model fits

Dose-response profile of degradation of agrochemical using nasturtium

Heart rate baroreflexes for rabbits

The two-parameter log-logistic function

Glyphosate and metsulfuron-methyl tested on algae.

Printing key features

Mechlorprop and terbythylazine tested on Lemna minor

The Cedergreen-Ritz-Streibig model

The four-parameter Weibull functions

Dose-response model for estimation of no effect concentration (NEC).

Acifluorfen and diquat tested on Lemna minor.

Estimating effective doses

Simulating ED values under various scenarios

Bread and meat for the sandwich

Effect of technical grade and commercially formulated auxin herbicides

Extract fitted values from model

Effect of ferulic acid on growth of ryegrass

Effect of erythromycin on mixed sewage microorganisms

Creating isobolograms

Data from toxicology experiments with selenium

Lack-of-fit test for the mean structure based on cumulated residuals

Expected or predicted response

The two-parameter Weibull functions

The five-parameter log-logistic function

Maximum mean response

S.capricornutum

Effect of cadmium on growth of green alga

Transform-both-sides Box-Cox transformation

Potency of two herbicides

Germination of common chickweed (Stellaria media)

Mean function for the Gompertz dose-response or growth curve

Earthworm toxicity test

The effect of terbuthylazin on growth rate

The Brain-Cousens hormesis models

Summarising non-linear model fits

Deguelin applied to chrysanthemum aphis

Germination of three crops

Log-normal dose-response model

Fractional polynomial-logistic dose-response models

Asymptotic regression model

Calculating yield loss parameters

Inhibition of photosynthesis

Model selection

Estimation of ED values using model-averaging

Extracting residuals from model

Mizon-Richard test for dose-response models

Assessing the model fit

Test data from a 21 day fish test

The three-parameter log-logistic function

Weibull model functions

Simulating a dose-response curve

Model-robust dose-response modelling

The derivative of the Gompertz function

Updating and re-fitting a model

Fitting binary mixture models

Volume of algae as function of increasing concentrations of a herbicide

Michaelis-Menten model

The modified baro5 function

The Brain-Cousens hormesis models

Example of plant growth curve from Covarelli and Onofri (1998)

The log-logistic function

Plotting fitted curves for a 'drc' or 'mrdrc' object

print.summary.drc

Printing summary of non-linear model fits

Exponential decay model

Herbicide applied to Galium aparine

Mortality of tobacco budworms

The four-parameter log-logistic function

Effect of an effluent on the growth of mysid shrimp

Leaf length of barley

Competition between two biotypes

Sets control arguments

Showing starting values used

getMeanFunctions

Display available dose-response models

Gompertz growth models

Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction

Two-phase dose-response model