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drc (version 2.3-7)

Analysis of dose-response curves

Description

Analysis of dose-response curves in biology, environmental sciences, medicine, pharmacology, toxicology

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Version

Install

install.packages('drc')

Monthly Downloads

58,200

Version

2.3-7

License

GPL-2

Maintainer

Christian Ritz

Last Published

April 18th, 2013

Functions in drc (2.3-7)

SI

Comparing selectivity indices across curves
gaussian

Normal and log-normal biphasic dose-response models
modelFit

Assessing the model fit
summary.drc

Summarising non-linear model fits
ryegrass

Effect of ferulic acid on growth of ryegrass
leaflength

Leaf length of barley
mrdrm

Model-robust dose-response modelling
S.capricornutum

Effect of cadmium on growth of green alga
getInitial

Showing starting values used
spinach

Inhibition of photosynthesis
deguelin

Deguelin applied to chrysanthemum aphis
P.promelas

Effect of sodium pentachlorophenate on growth of fathead minnow
AR

Asymptotic regression model
yieldLoss

Calculating yield loss parameters
lettuce

Hormesis in lettuce plants
braincousens

The Brain-Cousens hormesis models
LL.2

The two-parameter log-logistic function
selenium

Data from toxicology experiments with selenium
secalonic

Root length measurements
predict.drc

Prediction
terbuthylazin

The effect of terbuthylazin on growth rate
acidiq

Acifluorfen and diquat tested on Lemna minor.
mr.test

Mizon-Richard test for dose-response models
beetGrowth

Example of plant growth curve from Covarelli and Onofri (1998)
drmc

Sets control arguments
residuals.drc

Extracting residuals from the fitted dose-response model
PR

Expected or predicted response
boxcox.drc

Transform-both-sides Box-Cox transformation
simDR

Simulating ED values under various scenarios
lepidium

Dose-response profile of degradation of agrochemical using lepidium
cedergreen

The Cedergreen-Ritz-Streibig model
mselect

Dose-response model selection
isobole

Creating isobolograms
EXD

Exponential decay model
NEC

Dose-response model for estimation of no effect concentration (NEC).
W1.4

The four-parameter Weibull functions
drm

Fitting dose-response models
daphnids

Daphnia test
CRS.4a

The Cedergreen-Ritz-Streibig model
getMeanFunctions

Display available dose-response models
M.bahia

Effect of an effluent on the growth of mysid shrimp
comped

Comparison of effective dose values
noEffect

Testing if there is a dose effect at all
S.alba

Potency of two herbicides
fplogistic

Fractional polynomial-logistic dose-response models
searchdrc

Searching through a range of initial parameter values to obtain convergence
auxins

Effect of technical grade and commercially formulated auxin herbicides
etmotc

Effect of erythromycin on mixed sewage microorganisms
MAX

Maximum mean response
print.summary.drc

Printing summary of non-linear model fits
W1.2

The two-parameter Weibull functions
O.mykiss

Test data from a 21 day fish test
bread.drc

Bread and meat for the sandwich
gompertzd

The derivative of the Gompertz function
ED.drc

Estimating effective doses
nasturtium

Dose-response profile of degradation of agrochemical using nasturtium
CRS.5a

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
vinclozolin

Vinclozolin from AR in vitro assay
germination

Germination of three crops
logistic

The logistic model
llogistic

The log-logistic function
earthworms

Earthworm toxicity test
weibull1

Weibull model functions
G.aparine

Herbicide applied to Galium aparine
LL.3

The three-parameter log-logistic function
MM

Michaelis-Menten model
RScompetition

Competition between two biotypes
confint.drc

Confidence Intervals for model parameters
glymet

Glyphosate and metsulfuron-methyl tested on algae.
maED

Estimation of ED values using model-averaging
finney71

Example from Finney (1971)
H.virescens

Mortality of tobacco budworms
heartrate

Heart rate baroreflexes for rabbits
baro5

The modified baro5 function
mixture

Fitting binary mixture models
LL.4

The four-parameter log-logistic function
fitted.drc

Extract fitted values from model
lnormal

Log-normal dose-response model
BC.5

The Brain-Cousens hormesis models
methionine

Weight gain for different methionine sources
neill.test

Neill's lack-of-fit test for dose-response models
ursa

Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
rdrm

Simulating a dose-response curve
plot.drc

Plotting fitted curves for a 'drc' or 'mrdrc' object
print.drc

Printing key features
vcov.drc

Calculating variance-covariance matrix for objects of class 'drc'
update.drc

Updating and re-fitting a model
LL.5

The five-parameter log-logistic function
anova.drc

ANOVA for dose-response model fits
algae

Volume of algae as function of increasing concentrations of a herbicide
coef.drc

Extract Model Coefficients
lin.test

Lack-of-fit test for the mean structure based on cumulated residuals
gompertz

Mean function for the Gompertz dose-response or growth curve
mecter

Mechlorprop and terbythylazine tested on Lemna minor
gompGrowth

Gompertz growth models
W1.3

The three-parameter Weibull functions
backfit

Calculation of backfit values from a fitted dose-response model
chickweed

Germination of common chickweed (Stellaria media)
diagnostics

Information on estimation
logLik.drc

Extracting the log likelihood
hatvalues.drc

Model diagnostics for nonlinear dose-response models
compParm

Comparison of parameters
twophase

Two-phase dose-response model