Learn R Programming
⚠️There's a newer version (3.0-1) of this package.Take me there.

drc (version 2.5-12)

Analysis of Dose-Response Curves

Description

Analysis of dose-response data is made available through a suite of flexible and versatile model fitting and after-fitting functions.

Copy Link

Version

Install

install.packages('drc')

Monthly Downloads

27,354

Version

2.5-12

License

GPL-2 | file LICENCE

Maintainer

Christian Ritz

Last Published

April 14th, 2015

Functions in drc (2.5-12)

W1.4

The four-parameter Weibull functions
W1.3

The three-parameter Weibull functions
coef.drc

Extract Model Coefficients
leaflength

Leaf length of barley
deguelin

Deguelin applied to chrysanthemum aphis
fplogistic

Fractional polynomial-logistic dose-response models
getInitial

Showing starting values used
cedergreen

The Cedergreen-Ritz-Streibig model
fitted.drc

Extract fitted values from model
ursa

Model function for the universal response surface approach (URSA) for the quantitative assessment of drug interaction
lepidium

Dose-response profile of degradation of agrochemical using lepidium
auxins

Effect of technical grade and commercially formulated auxin herbicides
algae

Volume of algae as function of increasing concentrations of a herbicide
glymet

Glyphosate and metsulfuron-methyl tested on algae.
lin.test

Lack-of-fit test for the mean structure based on cumulated residuals
llogistic

The log-logistic function
P.promelas

Effect of sodium pentachlorophenate on growth of fathead minnow
logLik.drc

Extracting the log likelihood
EDcomp

Comparing selectivity indices across curves
germination

Germination of three crops
W1.2

The two-parameter Weibull functions
nasturtium

Dose-response profile of degradation of agrochemical using nasturtium
spinach

Inhibition of photosynthesis
searchdrc

Searching through a range of initial parameter values to obtain convergence
H.virescens

Mortality of tobacco budworms
boxcox.drc

Transform-both-sides Box-Cox transformation
yieldLoss

Calculating yield loss parameters
daphnids

Daphnia test
LL.4

The four-parameter log-logistic function
gompertz

Mean function for the Gompertz dose-response or growth curve
NEC

Dose-response model for estimation of no effect concentration (NEC).
acidiq

Acifluorfen and diquat tested on Lemna minor.
comped

Comparison of effective dose values
ED.drc

Estimating effective doses
chickweed

Germination of common chickweed (Stellaria media)
gompertzd

The derivative of the Gompertz function
gaussian

Normal and log-normal biphasic dose-response models
print.drc

Printing key features
O.mykiss

Test data from a 21 day fish test
modelFit

Assessing the model fit
noEffect

Testing if there is a dose effect at all
bread.drc

Bread and meat for the sandwich
M.bahia

Effect of an effluent on the growth of mysid shrimp
drmc

Sets control arguments
summary.drc

Summarising non-linear model fits
weibull1

Weibull model functions
S.alba

Potency of two herbicides
anova.drc

ANOVA for dose-response model fits
compParm

Comparison of parameters
CRS.5a

Cedergreen-Ritz-Streibig dose-reponse model for describing hormesis
G.aparine

Herbicide applied to Galium aparine
logistic

The logistic model
LL.5

The five-parameter log-logistic function
EXD

Exponential decay model
lettuce

Hormesis in lettuce plants
finney71

Example from Finney (1971)
MM

Michaelis-Menten model
twophase

Two-phase dose-response model
backfit

Calculation of backfit values from a fitted dose-response model
vinclozolin

Vinclozolin from AR in vitro assay
baro5

The modified baro5 function
isobole

Creating isobolograms
etmotc

Effect of erythromycin on mixed sewage microorganisms
maED

Estimation of ED values using model-averaging
LL.3

The three-parameter log-logistic function
braincousens

The Brain-Cousens hormesis models
plot.drc

Plotting fitted dose-response curves
predict.drc

Prediction
secalonic

Root length measurements
earthworms

Earthworm toxicity test
mixture

Fitting binary mixture models
mselect

Dose-response model selection
selenium

Data from toxicology experiments with selenium
residuals.drc

Extracting residuals from the fitted dose-response model
gammadr

Gamma dose-response model
drm

Fitting dose-response models
BC.5

The Brain-Cousens hormesis models
AR

Asymptotic regression model
PR

Expected or predicted response
LL.2

The two-parameter log-logistic function
lnormal

Log-normal dose-response model
mr.test

Mizon-Richard test for dose-response models
mecter

Mechlorprop and terbythylazine tested on Lemna minor
print.summary.drc

Printing summary of non-linear model fits
neill.test

Neill's lack-of-fit test for dose-response models
CRS.4a

The Cedergreen-Ritz-Streibig model
diagnostics

Information on estimation
terbuthylazin

The effect of terbuthylazin on growth rate
MAX

Maximum mean response
RScompetition

Competition between two biotypes
confint.drc

Confidence Intervals for model parameters
S.capricornutum

Effect of cadmium on growth of green alga
heartrate

Heart rate baroreflexes for rabbits
getMeanFunctions

Display available dose-response models
methionine

Weight gain for different methionine sources
multi2

Multistage dose-response model with quadratic terms
ryegrass

Effect of ferulic acid on growth of ryegrass
hatvalues.drc

Model diagnostics for nonlinear dose-response models
update.drc

Updating and re-fitting a model
rdrm

Simulating a dose-response curve
vcov.drc

Calculating variance-covariance matrix for objects of class 'drc'
simDR

Simulating ED values under various scenarios